The Most Pressing Question(s) On Earth
I'd say there's no more pressing question than whether the largest US tech companies will deliver on the growth outlook implied by their valuation metrics, but that'd be... well, uncouth, let's call it.
There are certainly more pressing questions in the world than that. Here's an example: Is humanity staring at an accelerated climatic oblivion? The answer appears to be "yes," or at least "maybe," judging by catastrophes like what's unfolding in California.
Here's another example of a question