Amid Remdesivir Euphoria, Trump Plans ‘Operation Warp Speed’ For Vaccine

Amid Remdesivir Euphoria, Trump Plans ‘Operation Warp Speed’ For Vaccine

Even as the first read on Q1 GDP showed the US economy contracting more than expected, kicking off the first recession some market participants have seen in their adult lives, ostensible good news on the pandemic front stole the proverbial show Wednesday. Investors clamoring for an excuse to jump aboard as US stocks extend a furious bounce off the March lows, got it in the form of positive results from what Anthony Fauci described as "the first truly high-powered randomized placebo-controlled t
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18 thoughts on “Amid Remdesivir Euphoria, Trump Plans ‘Operation Warp Speed’ For Vaccine

  1. 2019: Trump gooses SPX on down days with tweets regarding make-believe progress on the trade war.

    2020: Trump gooses SPX on down days with tweets regarding make-believe progress on the vaccine development program.

  2. Remdesivir is a therapeutic not a vaccine. The results were 50% of the patients treated on a 5 day cycle showed meaningful improvement. However, there was no control group given a placebo so there is no way to know how many would have gotten better without any treatment at all. It may be effective but more trials would be necessary to confirm the initial indications of effectiveness. Whatever the case it is hopeful that there may be an effective therapy that significantly reduces the mortality rate, but enthusiasm should be tempered by the reality that it is not a cure or a vaccine. I agree that it was no accident that Gilead’s findings were disclosed right around the time of the GDP print –the bully pulpit has its perks

    1. Well said. And if I’m not mistaken, there has never been an FDA approved vaccine for any virus of the Corona family. But don’t let that get in the way of a good story. I appreciate the potential for Remdesivir to reduce deaths but today’s price action seems to have stemmed from misplaced hope…the last I checked, hope made for a terrible strategy.

      1. More details on the trial data that was released after the generic “hopium” headline. The Gilead study had a placebo control group. The result suggest a moderate but discernible benefit. 8% mortality for those on the drug 11% for those on the placebo. 11 days to recovery on the drug, 15 for the placebo. Will need to do more trials to factor for differences in the demography and the medical histories of the groups which are still relatively small by industry standards and too few to draw broad conclusions beyond “it helps some people” –how many and how much remains unclear.

        Then there are the pesky questions about production and distribution –is everyone going to have access the drug regardless of their ability to pay and regardless of the cost of the medication– if and when it becomes widely available?

      2. I read the first coronavirus was identified in 1968. And, there have been no approved vaccines (never mind “FDA approved”, but no approval anywhere) for any coronavirus to-date.

  3. “Vaccine development is typically slow and high risk. The project’s goal is to cut out the slow part, the people said . . ”

    Am I the only who appreciates the fact they want to keep the high risk part?

      1. Except you are really only going around in circles in NASCAR, so extremely risky, extremely fast, but you still end up in the same place – no vaccine.

        1. The way he’s been trotting out corporate leaders around the White House, it won’t be long before we get our “post race” interviews thanking each company between every 3 words.

          Oh, and car ran good. Like to thank the task force and the fine folks at Gilead for giving us the performance we needed down the back stretch.

          Lots of money in NASCAR, despite the ending where ya started.

          Sounds like he learned a lot driving backwards at Daytona, before the torrential downpour.

  4. I will be “safer at home” until I figure out what is going on.
    Carefully watching Sweden, South Korea and I really want to understand how things go in Italy with “opening up” before I get too carried away.

  5. Have not read about the wonder drug, yet, but I assume data is being fitted to goose results like, the best results are probably from people without underlying health conditions, who are in mid 30’s or something equally absurd. Any who has every watched drug trials understands that long term qualified data takes years, not weeks. Meanwhile as the virus mutates, Trump can focus on how the current death rate is a Democratic hoax, again!

  6. The remedsivir clinical trial data is decent. The NIAID trial was large, randomized, blinded, placebo controlled, and showed a statistically significant benefit that was modest, or moderate, depending on your point of view. It is consistent with what is known about the GILD trials. The Chinese trials were very underpowered and aborted, but the limited data at least rules out a major positive benefit. So the picture is getting clearer: moderate benefit, extreme unmet need, approval assured, and there will only be enough drug for maybe 140K patients until end of this year at earliest.

  7. From the NY Times:

    “…the idea would be to indemnify the major pharmaceutical and biotechnology companies from liability if the vaccines cause sickness or death…”

    Cool.

    1. I think they need congress for that step. I think, No more effective way to kill people than to remove all liability for human testing.

    2. “we can’t let the cure be worse than the disease” 1 month later “I don’t care how many lives it costs… cure the disease!” Actual words they wish they could say “humans are worthless, only money matters”.

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